1) Presentation & efficacy
NexGard is a chewable tablet for dogs based on afoxolaner. It quickly eliminates fleas (≈8 h) and ticks (≈48 h) and protects for 1 month. The oral, palatable form facilitates compliance: one monthly dose is sufficient, unaffected by baths/rain. Approved from 8 weeks and ≥ 2 kg. Precaution if neurological history: veterinary advice.
2) Exact dosage by weight
| Dog weight | Dosage | Box color | Frequency |
|---|---|---|---|
| 2–4 kg | 11.3 mg | Purple (XS) | 1 tablet / month |
| 4–10 kg | 28.3 mg | Orange (S) | 1 tablet / month |
| 10–25 kg | 68 mg | Blue (M) | 1 tablet / month |
| 25–50 kg | 136 mg | Green (L) | 1 tablet / month |
| > 50 kg | Combine several appropriate tablets | — | 1 time / month |
Give with or without food. If vomiting occurs < 2 h after administration, give another dose (consult if in doubt).
3) Indicative prices in France (updated 2025)
| Weight | Dosage | Pack. | Indicative price | Source |
|---|---|---|---|---|
| 2–4 kg | 11.3 mg | 6 tabs | ≈ €56.95 | La Pharmacie de Pierre |
| 4–10 kg | 28.3 mg | 3 tabs | ≈ €37.73 | Pharmacy4Pets |
| 10–25 kg | 68 mg | 6 tabs | ≈ €36.65 | Pharmacasse |
| 25–50 kg | 136 mg | 3 tabs | ≈ €43.55 | Pharmacasse |
4) Mode of action & tolerance
Afoxolaner (isoxazoline) inhibits GABA/glutamate channels in parasites → paralysis & death. Rapid absorption (Cmax ≈ 2–4 h), long half-life → monthly coverage. Side effects mainly digestive/skin, generally transient; very rare neurological signs in predisposed subjects. Avoid in puppies < 8 weeks, < 2 kg, pregnancy/lactation without professional advice.
5) Alternatives: comparison
| Product | Spectrum | Duration | Form | When to prefer |
|---|---|---|---|---|
| NexGard Spectra | Fleas, ticks + worms (intestinal/heart) | 1 month | Tablet | “All-in-one” protection |
| Simparica Trio | Fleas, ticks + worms | 1 month | Tablet | Complete alternative to Spectra |
| Bravecto | Fleas, ticks | ≈ 12 weeks | Tablet | Fewer doses per year |
| Seresto (collar) | Fleas, ticks | ≈ 8 months | Collar | Long continuous coverage |
| Advantix (spot-on) | Fleas, ticks, mosquitoes | 1 month | Spot-on | If you prefer external treatment |
6) Recommendation (order of preference)
- NexGard Spectra: best compromise of effectiveness/spectrum/simplicity.
- Simparica Trio: solid “all-in-one” alternative.
- NexGard (classic): targeted for fleas/ticks, palatable and reliable.
- Bravecto: convenient quarterly dose.
- Seresto or Advantix: non-oral options depending on use.
7) Quick FAQ
Prescription required in France? Yes, it is a veterinary medicine. What dosage for an 8 kg dog? 28.3 mg (4–10 kg range, orange box S). Difference between NexGard and NexGard Spectra? Spectra adds protection against internal worms (intestinal/heart).
8) Product photo gallery
9) Conclusion
NexGard combines effectiveness, simplicity, and good tolerance. For broader protection (including worms), NexGard Spectra or Simparica Trio should be preferred. In case of underlying diseases, always seek advice from the veterinarian.
